Education: Bachelor's degree or related field
Experience: 6+ years
What you'll do In your role as a Scientist, you will: - Collaborate with Single Cell Technology, Epigenetic Editing, and Predictive Modeling teams to design, build, and evaluate epigenetic reprogramming interventions for aged T cells, including integration and interpretation of complex, multi-modal datasets - Develop scalable functional assays in T cells and Tregs to predict therapeutic activity and inform lead selection - Design and lead in vivo and in vitro immunology studies to support target discovery, validation, and preclinical development - Contribute deep expertise in inflammatory and autoimmune disease biology to experimental design and data-driven program strategy - Drive research in Treg biology, including differentiation, stability, and suppressive function - Author or contribute to study reports, internal data packages, and regulatory-supporting documentation - Mentor junior scientists and foster a collaborative, rigorous scientific culture - Present data, analyses, and scientific recommendations clearly to internal teams and leadership
Requirements - Ph.D. in immunology, cell biology, or a related field or BS/MS with 6+ years of relevant industry experience - Hands-on experience with multi-parameter flow cytometry - Experience designing in vivo models of autoimmune or inflammatory disease - Experience with primary immune cell isolation, ex vivo culture, and Treg functional assay Nice to have - Experience with pooled in vitro or in vivo screening approaches using bulk or single-cell readouts (e.g., CRISPR fitness screens, Perturb-seq, CROP-seq) - Experience with rheumatoid arthritis and/or colitis models - Experience authoring IND-supporting study reports - Experience managing or partnering with CROs to support preclinical studies, including alignment on study design, timelines, and data quality - Familiarity with basic computational tools for data analysis (e.g., Python, R)
Benefits NewLimit offers generous benefits to ensure our team can focus on our mission: - Health, dental, and vision insurance - 401(k) with company match - Paid parental leave - Industry-leading paid time off (PTO) - 20 days/year for all employees + holidays - Meals and snacks on-site Salary Range: $130,000 to $180,000.
Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. NewLimit offers a competitive benefits package, which includes a 401k, healthcare coverage, and 20 days of PTO. Learn more at: https://www.newlimit.com/careers *This compensation and benefits information is based on Company's good faith estimate as of the date of publication and may be modified in the future.
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