Scientist, Drug Product Development

What you'll do - Formulate, purify, and characterize LNPs for nucleic acid delivery - Collaborate with the Epigenetic Editing and Product teams (Immunology, Metabolism, Vascular) to develop LNP-RNA reprogramming medicines. - Develop and optimize LNP compositions to target new cell types for reprogramming. - Interpret complex experimental data and perform statistical analyses to reach robust conclusions. - Maintain rigorous and detailed records of experimental protocols and results in an Electronic Laboratory Notebook (ELN).

Requirements - Ph.D. in Biomedical Engineering, Chemical Biology, Pharmaceutical Sciences, or a related discipline or equivalent industry experience - Experience formulating LNPs with diverse lipid components for nucleic acid delivery - Experience with purification techniques, including dialysis, Tangential Flow Filtration (TFF), ultracentrifugation, and sterile filtration. - Proficiency in LNP analysis using dynamic or multi-angle light scatting, liquid chromatography, and standard molecular biology assays (ELISA, qPCR, spectroscopy).

Nice to have - Experience contributing to drug product development at the preclinical or clinical stages. - Background in extra-hepatic nucleic acid delivery. - Experience with bioconjugation, surface modification, or targeted LNP formulation. - Experience with data visualization and statistical analysis (R, Python)

Benefits NewLimit provides generous benefits so our team can remain focused on our mission: - Comprehensive Health, Dental, and Vision insurance. - 401(k) plan with company match. - Paid parental leave. - Industry-leading PTO**:** 20 days per year plus holidays. - On-site meals and snacks. Salary Range: $113,000 to $171,000.

Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. NewLimit offers a competitive benefits package, which includes a 401k, healthcare coverage, and 20 days of PTO. Learn more at: https://www.newlimit.com/careers *This compensation and benefits information is based on Company's good faith estimate as of the date of publication and may be modified in the future.