Scientist/Senior Scientist, Immunology

- Collaborate with Single Cell Technology, Epigenetic Editing, and Predictive Modeling teams to design, build, and evaluate epigenetic reprogramming interventions for aged T cells, including integration and interpretation of complex, multi-modal datasets

- Develop scalable functional assays in T cells and Tregs to predict therapeutic activity and inform lead selection

- Design and lead in vivo and in vitro immunology studies to support target discovery, validation, and preclinical development

- Contribute deep expertise in inflammatory and autoimmune disease biology to experimental design and data-driven program strategy

- Drive research in Treg biology, including differentiation, stability, and suppressive function

- Author or contribute to study reports, internal data packages, and regulatory-supporting documentation

- Mentor junior scientists and foster a collaborative, rigorous scientific culture

- Present data, analyses, and scientific recommendations clearly to internal teams and leadership

- Ph.D. in immunology, cell biology, or a related field or BS/MS with 6+ years of relevant industry experience

- Hands-on experience with multi-parameter flow cytometry

- Experience designing in vivo models of autoimmune or inflammatory disease

- Experience with primary immune cell isolation, ex vivo culture, and Treg functional assay

- Experience with pooled in vitro or in vivo screening approaches using bulk or single-cell readouts (e.g., CRISPR fitness screens, Perturb-seq, CROP-seq)

- Experience with rheumatoid arthritis and/or colitis models

- Experience authoring IND-supporting study reports

- Experience managing or partnering with CROs to support preclinical studies, including alignment on study design, timelines, and data quality

- Familiarity with basic computational tools for data analysis (e.g., Python, R)

NewLimit offers generous benefits to ensure our team can focus on our mission:

- Health, dental, and vision insurance

- 401(k) with company match

- Paid parental leave

- Industry-leading paid time off (PTO) - 20 days/year for all employees + holidays

- Meals and snacks on-site

Salary Range: $130,000 to $180,000.

Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. NewLimit offers a competitive benefits package, which includes a 401k, healthcare coverage, and 20 days of PTO. Learn more at: https://www.newlimit.com/careers *This compensation and benefits information is based on Company's good faith estimate as of the date of publication and may be modified in the future.