Senior Manager, Statistical Programming - Job ID: 1646

Key

Responsibilities - Serve as the Statistical Programming Lead for clinical trials, overseeing all programming deliverables from study start to submission. - Represent Statistical Programming in cross-functional study team meetings and contribute to project planning and timelines. - Develop, validate, and maintain SDTM and ADaM datasets , following CDISC standards and study specifications. - Generate or validate tables, listings, and figures (TLFs) for clinical study reports, ISS/ISE, and regulatory submissions. - Support statisticians with planned and ad hoc analyses. - Develop and maintain reusable macros, templates, and specification tools to support consistent and efficient programming practices across studies. - Collaborate with cross-functional teams including Biostatistics, Data Management, and Medical Writing to ensure high-quality deliverables. - Ensure programming activities meet project timelines and quality expectations, following internal SOPs and industry best practices.

Requirements - Bachelor's degree in Statistics, Mathematics, Computer Science, or related field with at least 10 years of programming experience in the pharmaceutical or biotech industry; or a Master's degree with at least 7 years of relevant experience. - Proven experience as a lead programmer for clinical trials and complex technical projects. - Excellent knowledge of CDISC standards , including SDTM and ADaM. - Understanding of the clinical drug development process and regulatory requirements. - Proficiency in SAS programming, including the ability to develop and validate reusable macros . - Familiarity with other programming languages or tools (e.g., R , Python , Git , VB ) is a plus. - Experience contributing to departmental tools (e.g., macro libraries, specification templates, or automation tools) is preferred. - Strong verbal and written communication skills, with the ability to collaborate effectively across functions. - Self-motivated and detail-oriented, with the ability to manage multiple tasks and adapt to shifting priorities under tight deadlines.

Salary Range: $170-180K/year A note to recruiters: We do not allow external search party solicitation. Presentation of candidates without written permission from the Ascendis Pharma Inc Human Resources team (specifically from: Talent Acquisition Partner or Human Resources Director) is not allowed. If this occurs your ownership of these candidates will not be acknowledged.

Benefits - 401(k) plan with company match - Medical, dental, and vision plans - Company-offered Life and Accidental Death & Dismemberment (AD&D) insurance - Company-provided short and long-term disability

benefits - Unique offerings of Pet Insurance and Legal Insurance - Employee Assistance Program - Employee Discounts - Professional Development - Health Saving Account (HSA) - Flexible Spending Accounts - Various incentive compensation plans - Accident, Critical Illness, and Hospital Indemnity Insurance - Mental Health resources - Paid leave benefits for new parents