Associate Principal Scientist, Process Chemistry

The Process Chemistry organization located at our Rahway, NJ site is seeking a highly motivated and accomplished process chemist to play a key role in advancing our pipeline of drug substances, including small molecules, macrocyclic peptides, and bioconjugates. This position offers an opportunity to provide scientific leadership in the design and development of efficient, scalable, and robust manufacturing processes from discovery through commercialization.

The successful candidate will lead the development of innovative synthetic routes and practical manufacturing processes, drive critical technical and strategic decisions across programs, and influence the advancement of process chemistry capabilities within the organization.

Responsibilities include identifying and implementing enabling technologies, solving complex chemistry challenges, leading cross-functional collaborations, supporting technology transfers, and mentoring junior scientists. The candidate will also be expected to contribute to the external scientific community through publications, patents, presentations, and professional engagement.

The ideal candidate will possess deep expertise in synthetic organic chemistry and process development, a proven record of scientific innovation and technical achievement, and the ability to operate effectively in a highly collaborative and dynamic environment.

- Provide scientific leadership for the design, development, and optimization of scalable chemical processes across multiple development programs and modalities.

- Lead the resolution of complex chemistry and manufacturing challenges through innovative process design and mechanistic understanding.

- Develop practical, robust, and cost-effective manufacturing routes suitable for clinical and commercial supply.

- Drive process characterization, optimization, scale-up, and technology transfer activities in collaboration with analytical, engineering, manufacturing, quality, and regulatory partners.

- Influence project strategy and key technical decisions through strong scientific insight and data-driven recommendations.

- Identify and implement emerging technologies and modern synthetic methodologies to enhance process efficiency and capability.

- Mentor and develop scientists within the department while fostering a culture of scientific excellence, innovation, and collaboration.

- Represent Process Chemistry on cross-functional teams and effectively communicate technical strategies and project outcomes to senior leadership and external stakeholders.

- Contribute to the scientific community through publications, patents, presentations, and professional service activities.

- Minimum of 4 years of relevant industrial experience following completion of a Ph.D., with demonstrated success in small molecule process chemistry.

- Proven track record of scientific excellence and significant research accomplishments in synthetic organic chemistry and process development.

- Strong expertise in synthetic organic chemistry, reaction design, and mechanistic understanding.

- Demonstrated creativity, innovation, and scientific rigor in solving complex chemistry challenges.

- Proven ability to develop practical, scalable, and commercially viable chemical processes.

- Strong laboratory productivity, technical execution, and data interpretation skills.

- Demonstrated success in advancing process chemistry programs from early development through late-stage development and/or commercialization.

- Excellent written and verbal communication skills, with the ability to effectively communicate technical concepts to scientific and non-scientific audiences.

- Strong collaboration and interpersonal skills, with the ability to work effectively across multidisciplinary teams and global organizations.

- Demonstrated ability to lead and influence cross-functional teams, drive strategy, and shape scientific decision-making.

- Proven record of mentorship, talent development, and technical leadership.

- Demonstrated external scientific impact through publications, patents, presentations, and participation in the broader scientific community.

Required Skills: Analytical Chemistry, Analytical Development, Chemical Processes, Chemical Processing, Chemical Products, Chemical Synthesis, Clinical Judgment, Computational Chemistry, Data Analysis, Enzymology, Evidence Based Decision Making, Experimental Development, Lead Optimization, Molecular Structure, Multidisciplinary Collaboration, Organic Chemistry, Synthetic Chemistry, Technology Transfer, US Patent

Job Posting End Date: 09/7/2026 *A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.