Senior Director, Portfolio Integration Lead - Hematology

- Shape the advancement of multiple development programs within the oncology portfolio by providing scientific insights across assets, ensuring that agreed disease strategy is implemented consistently across programs.

- Prepare detailed strategic analyses and portfolio recommendations on behalf of the Disease Area Vice President, enabling effective decision-making at senior leadership and governance levels.

- Ensure alignment and coordination across Clinical Matrix Teams (CMTs) and relevant cross-functional stakeholders in Research & Development (R&D), Global Medical Affairs (GMA) and Global Product Strategy (GPS).

- Drive disease-level strategic discussions and portfolio planning, bringing a pan-asset perspective to governance discussions and portfolio prioritization.

- Serve as a subject matter expert supporting global health authority interactions, regulatory submissions and key development milestones across multiple assets.

- Serve as a scientific thought partner to CDLs across multiple asset programs, shaping key aspects of clinical development strategy for a given tumour types, including:

- Establish and champion consistent ways of working across programs to improve efficiency and development quality.

- Drive innovation in clinical development approaches for a given disease area, including trial design, novel endpoints, and emerging technologies such as AI-enabled analytics where appropriate.

- Maintain a deep understanding of the evolving tumour disease landscape, standards of care, and emerging science.

- Shape engagement with external experts through advisory boards.

- Synthesise portfolio-level external insights to inform and strengthen development strategy across multiple programs.

- Drive initiatives that strengthen the application of data, technology, and analytics in clinical development decision-making for a given tumour type.

- Champion innovative approaches to clinical trials and portfolio insights, ensuring the tumour portfolio remains at the forefront of emerging capabilities.

- Bachelor's / Master's / Advanced degree in a scientific or medical discipline. Candidates may come from a medical or scientific background; oncology drug development expertise with defined experience is expected.

- 10+ years of experience in oncology drug development within pharmaceutical or biotechnology environments, including involvement across multiple programs or assets.

- Experience of clinical development processes, regulatory pathways, and oncology therapeutic landscapes.

- Experience in operating structured matrix organizations and demonstrate decision-making and stakeholder engagement at senior organizational levels.

- Experience as a Clinical Development Lead, Medical Director, Clinical Scientist Program Lead, or equivalent program leadership role in oncology.

- Expertise in biomarker development, precision medicine strategies, or combination therapy approaches.

- Experience engaging with external scientific experts, advisory groups, and Health Authorities.

- Demonstrated ability to influence senior stakeholders and shape strategic portfolio discussions.

- Familiarity with clinical trial innovation methods, including AI/ML applications, adaptive trial designs, or real-world evidence integration.

Work Arrangement: This role offers a hybrid working model, with a mix of on-site and remote work. Remote or fully home-working arrangements are not available for this role.

Skills Clinical Data Interpretation, Clinical Trial Designs, Clinical Trials Monitoring, Digital Fluency, Drug Development, Drug Regulatory Affairs, Evidence Based Decision Making, Executive Presence, Hematology and Oncology, Learning Agility, Matrix Leadership, Real World Evidence (RWE), Scientific Presentations, Strategic Direction

- If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $242,250 to $403,750. The US salary ranges take into account a number of factors including work location within the US market, the candidate's skills, experience, education level and the market rate for the role.

In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.

If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.