Senior Associate Scientist - Oncology Discovery

Working with Us Challenging. Meaningful. Life-changing.

Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department.

From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment.

We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. : careers.bms.com/working-with-us .

The Protein Homeostasis Thematic Research Center at BMS is a fundamental Oncology research engine delivering oncology and hematology therapeutics to patients. The TRC has a major focus on exploiting BMS’ expertise in protein degradation to discover and develop therapies aimed at tumor intrinsic vulnerabilities and mechanisms of resistance to existing cancer therapeutics.

This focus on protein degradation allows us to attack protein classes that were previously deemed undruggable.

In the role as a Senior Associate Scientist within Oncology Discovery, the ideal candidate:

• Designs and executes experiments based on cell and molecular biology protocols

• Prepares and presents experimental results to project team leaders

• Works within established procedures to perform large-scale cell-based assays and screens

• Actively participates in troubleshooting to implement data-driven solutions to cell engineering challenges and optimize NGS library protocols to utilize new technologies

• Coordinates activities with other team members to achieve results

• Bachelor’s Degree and 4+ years of academic and / or industry experience

• Master’s Degree and 2+ years of academic and / or industry experience

• Expertise across multiple gene editing platforms, including CRISPR/Cas9 and Perturb-seq, with direct experience in guide RNA design and verification of editing outcomes (i.e. genomic cleavage assays, flow cytometry-based reporters, etc.)

• Experience designing and executing NGS library preparation workflows for gene editing applications and CRISPR screens with a focus on optimization for improved efficiency

• Skilled in both large-scale and single-cell CRISPR screen-enabling studies, including molecular cloning and plasmid design, cell engineering, lentiviral transduction, flow cytometry, western blot/JESS Simple Western, amplicon PCR, and large-format multilayer-flask tissue culture

• Experience supporting oncology drug discovery pipelines through design and execution of cell-based assays with a focus on genetic-perturbation strategies to interrogate novel therapeutic targets

• Ability to effectively communicate scientific findings to cross-functional teams

• Proficiency using scientific data analysis programs including GraphPad Prism, FlowJo, Microsoft Excel and PowerPoint, Geneious, Benchling, TapeStation Analysis Software

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience.

Final, individual compensation will be decided based on demonstrated experience.

• Health Coverage: Medical, pharmacy, dental, and vision care.

• Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).

• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.

• US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)

• Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays

Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture.

For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com .

Visit careers.bms.com/ eeo -accessibility to access our complete Equal Employment Opportunity statement.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection .

If you believe that the job posting is missing information required by local law or incorrect in any way, please contact BMS at TAEnablement@bms.com . Please provide the Job Title and Requisition number so we can review. Communications related to your application should not be sent to this email and you will not receive a response.

Inquiries related to the status of your application should be directed to Chat with Ripley.