Principal Program Manager, Process Safety & Risk

The Opportunity The Principal Program Manager, Process Safety & Risk will apply advanced theoretical knowledge and contribute to the development of new principles and concepts to independently address unusually complex or strategic problems. To excel in this position, the ideal candidate will possess 8+ years of progressive experience and a unique blend of strong technical expertise, exceptional leadership skills, and strategic agility.

Key Responsibilities Drive a multi-year Process Safety and SHE Risk Management strategy that directly aligns with the site's mission to deliver life-saving drug substances. Exercise high-level autonomy and independent judgment to shape the organization's long-range goals and significant strategic outcomes. Lead root-cause analysis and complex incident investigations, applying innovative engineering solutions to ensure a path toward zero injuries and illnesses.

Ensure strict adherence to Roche Corporate SHE Directives (including K3 and K9) by developing and continuously improving comprehensive risk management programs. Serve as the primary cross-functional liaison, effectively partnering with manufacturing, engineering, production services, warehouse, and quality teams in addition to contractors and service providers to ensure the successful execution of site-wide safety initiatives.

Act as a key organizational spokesperson, synthesizing complex technical data into clear, persuasive messages to influence stakeholders and drive policy adoption. Champion operational efficiency by managing budgets, schedules, and change management efforts that reframe safety challenges into sustainable business opportunities.

Who You Are Bachelor's degree in chemical, mechanical, civil, or electrical engineering. Certification as a registered professional engineer is preferred, but not required. 8+ years of relevant work experience in SHE program management, process safety engineering, or risk management.

Prior experience in the Biotechnology and Pharmaceutical industries or high-hazard environments is preferred. Extensive "hands-on" experience in leading process safety reviews, conducting safety risk assessments, and developing strategic control solutions using engineering and administrative controls. Extensive in-the-field experience conducting incident investigations and root-cause analysis.

Thorough knowledge of environment, health, and safety regulations, codes, and standards, including Cal/OSHA, OSHA, EPA, NIOSH, Cal/ARP, and local CUPA requirements. Excellent teamwork skills with the ability to effectively lead, facilitate, and motivate cross-functional and interdepartmental agile teams in a fast-paced environment.

Location This position is based in South San Francisco, CA campus Relocation assistance is not available at this time. The expected salary range for this position based on the primary location of South San Francisco, CA is $138,500.00- 257,100.00 USD. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.

A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants. Who We Are Genentech, a member of the Roche group and founder of the biotechnology industry, is dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases.

To solve the world's most complex health challenges, we ask bigger questions that challenge our industry and the boundaries of science to transform society. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis. The next step is yours.

To apply today, click on the "Apply for this job" button. Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence.

The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.